(R)-Benzyl 3-aminopiperidine-1-carboxylate

Name: (R)-Benzyl 3-aminopiperidine-1-carboxylate
Brand: ChemScene
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CAS No. 1044560-96-4
Cat. No. CS-W003252
Purity≥95%
MDL No.MFCD05864625

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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(R)-Benzyl 3-aminopiperidine-1-carboxylate|CS-W003252

Structure of 1044560-96-4

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Description

(R)-Benzyl 3-aminopiperidine-1-carboxylate features a chiral piperidine core with a strategically positioned amino group, enabling direct functionalization in asymmetric synthesis. The benzyl ester moiety offers enhanced stability and solubility under standard reaction conditions, facilitating efficient incorporation into complex molecular architectures. This configuration supports high diastereoselectivity in downstream transformations.

Application

(R)-Benzyl 3-aminopiperidine-1-carboxylate serves as a versatile chiral building block in medicinal chemistry, enabling efficient access to piperidine-based scaffolds. Its amine and ester functionalities support diverse transformations, including reductive amination, acylation, and coupling reactions. The (R)-configuration provides stereochemical control for targeted synthesis of bioactive molecules. Bench-stable and readily purified, it functions effectively in standard peptide and small-molecule synthesis workflows.

General Information

CAS No. 1044560-96-4
Cat. No. CS-W003252
Purity ≥95%
MDL No. MFCD05864625
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₃H₁₈N₂O₂
Molecular Weight 234.29
Synonym(s) (R)-1-Cbz-3-aminopiperidine
SMILES N[C@@H]1CCCN(C1)C(=O)OCc1ccccc1

Computational Chemistry Data

TPSA 55.56
LogP 1.7463
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Ester

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-Benzyl 3-aminopiperidine-1-carboxylate

CAS No. 1044560-96-4

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