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Structure of 105614-25-3
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This bench-stable difluorocyclopropanamine hydrochloride features a strained cyclopropane ring bearing two fluorine atoms and a primary amine group, enabling direct incorporation into bioactive molecules. The trifluoromethyl-like electronic profile enhances metabolic stability while maintaining favorable binding interactions in target-directed synthesis.
2,2-Difluorocyclopropan-1-amine hydrochloride serves as a stable, bench-ready building block for fluorinated heterocycles and bioactive molecule synthesis. Its strained cyclopropane core enables regioselective ring-opening reactions, while the amine functionality supports straightforward derivatization via alkylation, acylation, or coupling protocols. The difluoro substitution enhances metabolic stability and modulates electronic properties, making it valuable in medicinal chemistry workflows targeting CNS agents and kinase inhibitors.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: