(1R,2S)-2-Fluorocyclopropan-1-amine hydrochloride

Name: (1R,2S)-2-Fluorocyclopropan-1-amine hydrochloride
Brand: ChemScene
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CAS No. 141042-21-9
Cat. No. CS-0101187
Purity≥95%
MDL No.MFCD09258983

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FedEx Limited Quantities Ground	$0.00
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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(1R,2S)-2-Fluorocyclopropan-1-amine hydrochloride|CS-0101187

Structure of 141042-21-9

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Description

This fluorinated cyclopropanamine derivative features a strained three-membered ring with stereocontrolled fluorine and amine substituents, enabling precise incorporation into bioactive scaffolds. The hydrochloride salt enhances solubility and stability under standard handling conditions, facilitating use in medicinal chemistry and synthetic methodology development.

Application

(1R,2S)-2-Fluorocyclopropan-1-amine hydrochloride serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of fluorinated cyclopropyl-containing scaffolds prevalent in bioactive molecules. Its bench-stable hydrochloride salt facilitates handling and purification, while the stereodefined fluorine and amine groups offer predictable reactivity in nucleophilic substitution, coupling, and cyclization processes. Functions effectively in standard synthetic workflows for drug discovery and process development.

General Information

CAS No. 141042-21-9
Cat. No. CS-0101187
Purity ≥95%
MDL No. MFCD09258983
Storage Store at room temperature, keep dry and cool
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₃H₇ClFN
Molecular Weight 111.55
Synonym(s) cis-2-fluorocyclopropylaminetosylate
SMILES N[C@H]1[C@@H](F)C1.Cl

Computational Chemistry Data

TPSA 26.02
LogP 0.4773
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Other Classifications

Building Blocks Functional Group Fluoride

Building Blocks Skeleton Fatty ring compounds Cyclopropane compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

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(1R,2S)-2-Fluorocyclopropan-1-amine hydrochloride

CAS No. 141042-21-9

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