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Structure of 1060739-01-6
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2,5-Difluoro-4-methoxybenzoic acid features a strategically positioned trifunctional aromatic core with electron-withdrawing fluorine atoms and a methoxy group enhancing solubility and metabolic stability. This configuration enables direct integration into pharmaceutical scaffolds and synthetic intermediates requiring precise electronic tuning and orthogonal reactivity.
2,5-Difluoro-4-methoxybenzoic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of fluorinated aromatic scaffolds common in bioactive molecules. Its orthogonal functionality—combining electron-withdrawing fluorine atoms with a methoxy group and a carboxylic acid—facilitates diverse downstream transformations, including amide coupling, esterification, and Suzuki-Miyaura cross-coupling. The compound exhibits good bench stability and is readily purified by recrystallization, making it well-suited for high-throughput screening campaigns and process-scale applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: