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CS-W001157 4
Total: USD 88.00

4-Amino-2,2-difluoro-1,3-benzodioxole

  • CAS No. 106876-54-4

  • Cat. No. CS-W017560
  • Purity≥98%
  • MDL No.MFCD00792416

*For research and further manufacturing use only, not for direct human use.

4-Amino-2,2-difluoro-1,3-benzodioxole|CS-W017560

Structure of 106876-54-4

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General Information

  • CAS No. 106876-54-4
  • Cat. No. CS-W017560
  • Purity ≥98%
  • MDL No. MFCD00792416
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅F₂NO₂
  • Molecular Weight 173.12
  • Synonym(s) 4-AMINO-2,2-DIFLUOROBENZODIOXOLE
  • SMILES NC1=CC=CC2=C1OC(F)(F)O2

Description

N-Mal-N-bis(PEG2-t-butyl ester) is a branched maleimide ester. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The t-butyl pester can be hydrolyzed under mild acidic conditions.

Synthesis

  • Route1
    • 5,6-Dichloro-2,2-Difluoro-4-nitro-benzo[1,3]dioxole|CS-0744592
      149045-81-8
    • ~%
    • In-stock
      4-Amino-2,2-difluoro-1,3-benzodioxole|CS-W017560
      106876-54-4

    References

    • US5260460 A1, ;
  • Route2
    • null|null
      106876-53-3
    • ~%
    • In-stock
      4-Amino-2,2-difluoro-1,3-benzodioxole|CS-W017560
      106876-54-4

    References

    • US4722935 A1, ;
  • Route3

    References

    • Schlosser, Manfred; Gorecka, Joanna; Castagnetti, Eva European Journal of Organic Chemistry, 2003 , # 3 p. 452 - 462

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2810
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H311-H315-H319-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   44.48
  • LogP   1.5903
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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