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Structure of 106877-31-0
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3-Methyl-4-(trifluoromethyl)aniline features a trifluoromethyl group that imparts enhanced electron-withdrawal and metabolic stability, while the methyl substituent provides steric influence. This combination enables efficient incorporation into pharmaceutical scaffolds and advanced materials. The compound exhibits robust bench stability and facilitates direct coupling in cross-coupling reactions under standard conditions.
3-Methyl-4-(trifluoromethyl)aniline serves as a valuable building block in medicinal chemistry and agrochemical synthesis, offering enhanced lipophilicity and metabolic stability through its trifluoromethyl group. The aniline functionality enables direct coupling reactions, while the methyl substituent provides steric and electronic modulation. Its bench-stable solid form facilitates handling and purification, making it well-suited for multistep syntheses requiring functional group tolerance and predictable reactivity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H320-H335
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Precautionary Statements : P264-P270-P330
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Lot numbers can be found on the outside label of a product: