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Structure of 1073266-02-0
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This rel-((1R,4R)-4-(trifluoromethyl)cyclohexanamine) features a rigid, stereodefined cyclohexane scaffold with a trifluoromethyl group at the C4 position, conferring enhanced lipophilicity and metabolic stability. The amine functionality enables straightforward derivatization for medicinal chemistry applications.
rel-((1R,4R)-4-(Trifluoromethyl)cyclohexanamine) serves as a valuable chiral building block in medicinal chemistry, enabling the construction of bioactive heterocycles and pharmaceutical scaffolds. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the cyclohexanamine core provides a rigid, stereochemically defined platform for functionalization. The compound exhibits excellent bench stability and compatibility with standard coupling and reduction protocols, facilitating efficient synthesis of target molecules in drug discovery campaigns.
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GHS Pictogram :
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GHS No : GHS02,GHS05
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Signal Word : Danger
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UN#: 2734
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Class : 8 (3)
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Packing Group : Ⅱ
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Hazard Statements : H226-H314
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Precautionary Statements : P210-P233-P240-P241-P242-P264-P280-P301+P330+P331-P304+P340-P370+P378-P405
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Lot numbers can be found on the outside label of a product: