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Structure of 1073354-58-1
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This boronate ester features a (E)-configured difluorostyryl group conjugated to a stable tetramethyl-1,3,2-dioxaborolane moiety. The electron-deficient olefin enhances reactivity in Suzuki-Miyaura couplings, while the sterically protected boron center ensures bench-stable handling and compatibility with diverse reaction conditions.
(E)-2-(3,5-Difluorostyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane serves as a stable, bench-ready boronate building block for Suzuki-Miyaura cross-coupling reactions. Its (E)-configured vinylborane moiety enables efficient coupling with aryl and heteroaryl halides, facilitating the construction of biaryl and styrenyl scaffolds prevalent in pharmaceutical and agrochemical research. The tetramethyl-substituted dioxaborolane ring enhances stability and simplifies purification, while the 3,5-difluorophenyl group offers predictable electronic effects and orthogonal reactivity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: