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CS-W001157 4
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5-Amino-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole-4-carbonitrile

  • CAS No. 1082745-49-0

  • Cat. No. CS-M0340
  • Purity≥98%
  • MDL No.MFCD12405838

*For research and further manufacturing use only, not for direct human use.

5-Amino-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole-4-carbonitrile|CS-M0340

Structure of 1082745-49-0

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General Information

  • CAS No. 1082745-49-0
  • Cat. No. CS-M0340
  • Purity ≥98%
  • MDL No. MFCD12405838
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₂N₄O
  • Molecular Weight 192.22
  • Synonym(s) 5-AMino-1-(tetrahydro-pyran-4-yl)-1H-pyrazole-4-carbonitrile
  • SMILES N#CC1=C(N)N(C2CCOCC2)N=C1

Synthesis

  • Route1
    • 2-(Ethoxymethylene)propanedinitrile|CS-0653697
      123-06-8
    • In-stock
      (Tetrahydro-2H-pyran-4-yl)hydrazine|CS-B0289
      116312-69-7
    • ~36%
    • In-stock
      5-Amino-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole-4-carbonitrile|CS-M0340
      1082745-49-0

    References

    • WO2009/121919 A1, ; Page/Page column 180 ; WO 2009/121919 A1
  • Route2

    References

    • Journal of Medicinal Chemistry, , vol. 55, # 21 p. 9045 - 9054
  • Route3

    References

    • Journal of Medicinal Chemistry, , vol. 55, # 21 p. 9045 - 9054

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   76.86
  • LogP   0.68848
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   1

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