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Structure of 108957-75-1
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Diethyl 3,5-dimethoxybenzylphosphonate features a benzylphosphonate core with two methoxy groups at the 3- and 5-positions, enhancing electronic delocalization and stability. This bench-stable reagent integrates readily into C–C bond-forming reactions, particularly in Horner–Wadsworth–Emmons olefination sequences. The electron-rich aromatic ring supports efficient coupling under mild conditions.
Diethyl 3,5-dimethoxybenzylphosphonate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to functionalized benzylphosphonates via standard Pudovik or Horner-Wadsworth-Emmons reactions. The 3,5-dimethoxy substitution enhances electron density at the aromatic ring, promoting stability and facilitating electrophilic functionalization. Its bench-stable nature and compatibility with diverse reaction conditions make it well-suited for iterative synthesis of complex scaffolds, including those relevant to medicinal chemistry and agrochemical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: