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Structure of 1092491-37-6
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This chiral phosphine ligand features a sterically hindered, electron-rich bis(trifluoromethyl)phenylphosphanyl group paired with a dihydrooxazole scaffold and tert-butyl substituent. The configuration at the 2-position ensures high enantioselectivity in palladium-catalyzed cross-coupling reactions. Its bench-stable nature enables reliable performance under standard conditions.
(S)-2-(2-(Bis(3,5-bis(trifluoromethyl)phenyl)phosphanyl)phenyl)-4-(tert-butyl)-4,5-dihydrooxazole serves as a robust, bench-stable ligand in palladium-catalyzed cross-coupling reactions. Its sterically encumbered bis(trifluoromethyl)phenylphosphine moiety enhances oxidative stability and promotes efficient catalytic turnover, while the dihydrooxazole ring provides structural rigidity and favorable coordination geometry. This ligand enables high-yielding couplings under mild conditions with broad functional group tolerance.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: