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Structure of 109299-79-8
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This boronate moiety integrates a sterically shielded pyrimidine core, enabling robust coupling in Suzuki-Miyaura reactions. The 2,4-di-tert-butoxy substitution pattern enhances solubility and stability under standard conditions, while the para-boronate functionality facilitates efficient C–C bond formation with aryl halides.
(2,4-Di-tert-butoxypyrimidin-5-yl)boronic acid serves as a stable, bench-friendly building block for constructing pyrimidine-based scaffolds via Suzuki-Miyaura coupling. Its ortho-di-tert-butyl substitution enhances solubility and minimizes protodeboronation, enabling reliable cross-coupling with aryl and heteroaryl halides under standard conditions. The boronic acid functionality exhibits high functional group tolerance and facilitates the synthesis of complex heterocyclic architectures relevant to medicinal chemistry and agrochemical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: