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Structure of 1093847-80-3
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6-Ethynyl-1H-indazole is a bench-stable, moisture-tolerant heterocyclic building block featuring a terminal alkyne group at the 6-position of the indazole core. This functionality enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) for conjugation in bioorthogonal labeling and click chemistry applications. The electron-deficient indazole scaffold supports diverse downstream transformations in medicinal chemistry and materials science.
6-Ethynyl-1H-indazole serves as a versatile building block in synthetic organic chemistry, enabling efficient access to functionalized heterocycles via copper-catalyzed coupling reactions. Its terminal alkyne moiety facilitates reliable Sonogashira and click-type conjugations, while the indazole core provides inherent stability and compatibility with diverse reaction conditions. The compound exhibits excellent bench stability, ease of purification, and broad functional group tolerance, making it well-suited for medicinal chemistry lead optimization and the construction of complex API scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H320-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: