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Structure of 110099-94-0
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2-(Methylthio)pyrimidine-5-carboxylic acid features a pyrimidine core functionalized with a methylthio group at the 2-position and a carboxylic acid at the 5-position. This combination delivers enhanced solubility and reactivity, enabling direct incorporation into pharmaceutical intermediates. The electron-withdrawing carboxylic acid paired with the electron-donating methylthio moiety creates a polarized system ideal for cross-coupling reactions and bioconjugation workflows under standard conditions.
2-(Methylthio)pyrimidine-5-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of pyrimidine-based heterocycles through standard functional group transformations. Its carboxylic acid moiety facilitates amide coupling and esterification, while the methylthio group offers moderate stability and compatibility with common reaction conditions. The molecule functions effectively in scaffold elaboration for kinase inhibitors and other bioactive compounds, offering predictable reactivity in standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: