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CS-W001157 4
Total: USD 88.00

Benzofuran-6-amine

  • CAS No. 110677-54-8

  • Cat. No. CS-0102042
  • Molecule weight133.15
  • Purity≥97%
  • MDL No.MFCD11110252

*For research and further manufacturing use only, not for direct human use.

Benzofuran-6-amine|CS-0102042

Structure of 110677-54-8

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General Information

  • CAS No. 110677-54-8
  • Cat. No. CS-0102042
  • Purity ≥97%
  • MDL No. MFCD11110252
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇NO
  • Molecular Weight 133.15
  • Synonym(s) 6-BENZOFURANAMINE
  • SMILES NC1=CC=C2C=COC2=C1

Description

Benzofuran-6-amine serves as a key heterocyclic scaffold in medicinal chemistry, offering a rigid, planar core with a primary amine at the 6-position. This functionality enables direct conjugation in Suzuki couplings and facilitates hydrogen bonding in target binding. The compound exhibits good solubility in common organic solvents and stability under standard bench conditions, supporting its use in synthetic route development and structure-activity studies.

Application

Benzofuran-6-amine serves as a versatile building block in medicinal chemistry, enabling the synthesis of heterocyclic scaffolds via standard coupling reactions. Its amine functionality facilitates rapid derivatization through amidation, alkylation, and electrophilic substitution, while the benzofuran core offers structural rigidity and favorable pharmacokinetic properties. The compound exhibits good bench stability and is readily purified by chromatography or recrystallization, supporting its use in both academic and industrial R&D workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P233-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

  • TPSA   39.16
  • LogP   2.015
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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