4-Amino-2,3-difluorobenzonitrile

Name: 4-Amino-2,3-difluorobenzonitrile
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 112279-71-7
Cat. No. CS-0134998
Purity≥98%
MDL No.MFCD09030642

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Amino-2,3-difluorobenzonitrile|CS-0134998

Structure of 112279-71-7

Size

Price

Quantity

* Please select Quantity before adding items.

Description

4-Amino-2,3-difluorobenzonitrile features a strategically positioned amino group flanked by two fluorine atoms and a nitrile functionality, enabling precise tuning of electronic properties. This combination enhances solubility and stability under standard conditions while facilitating efficient coupling reactions in medicinal chemistry applications.

Application

4-Amino-2,3-difluorobenzonitrile serves as a versatile building block in medicinal chemistry, enabling direct incorporation into diverse heterocyclic scaffolds via standard coupling and cyclization protocols. Its ortho-fluorine substituents facilitate nucleophilic aromatic substitution, while the amino and nitrile groups provide orthogonal reactivity for downstream functionalization. The compound exhibits good bench stability and is amenable to purification by recrystallization or chromatography, making it well-suited for scalable synthesis of kinase inhibitors and other bioactive molecules.

General Information

CAS No. 112279-71-7
Cat. No. CS-0134998
Purity ≥98%
MDL No. MFCD09030642
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₄F₂N₂
Molecular Weight 154.12
Synonym(s) 4-Amino-2,3-difluoro-benzonitrile
SMILES N#CC1=CC=C(C(F)=C1F)N

Computational Chemistry Data

TPSA 49.81
LogP 1.41868
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS06
Signal Word : Danger	UN#: 3439
Class : 6.1	Packing Group : Ⅲ
Hazard Statements : H301-H315-H319-H335
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Fluoride

Building Blocks Functional Group Cyanide/Nitrile

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

4-Amino-2,3-difluorobenzonitrile sigma4-Amino-2,3-difluorobenzonitrile manufacturer4-Amino-2,3-difluorobenzonitrile price4-Amino-2,3-difluorobenzonitrile structure4-Amino-2,3-difluorobenzonitrile SDSbuy 4-Amino-2,3-difluorobenzonitrile4-Amino-2,3-difluorobenzonitrile supplier4-Amino-2,3-difluorobenzonitrile uses4-Amino-2,3-difluorobenzonitrile molecular weightprice of 4-Amino-2,3-difluorobenzonitrile4-Amino-2,3-difluorobenzonitrile chemical name formula of 4-Amino-2,3-difluorobenzonitrile

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

4-Amino-2,3-difluorobenzonitrile

CAS No. 112279-71-7

Recommended Products