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Structure of 113162-36-0
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Methyl 4-fluoro-1H-indole-2-carboxylate features a fluorinated indole core with a methyl ester at the C2 position, offering enhanced electronic modulation and metabolic stability. This bench-stable compound integrates readily into synthetic routes for bioactive heterocycles, serving as a key intermediate in medicinal chemistry campaigns targeting CNS agents and kinase inhibitors.
Methyl 4-fluoro-1H-indole-2-carboxylate serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C4 position of the indole scaffold. The fluorine substituent enhances metabolic stability and modulates electronic properties, while the ester group facilitates downstream transformations such as hydrolysis, amidation, or coupling reactions. Its bench-stable nature and compatibility with standard cross-coupling protocols make it a practical choice for constructing complex heterocyclic architectures in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: