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Structure of 399-68-8
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4-Fluoro-1H-indole-2-carboxylic acid features a fluorinated indole core with a carboxylic acid group at the 2-position, enabling direct incorporation into bioactive molecule scaffolds. The electron-withdrawing fluorine substituent enhances metabolic stability and modulates electronic properties for medicinal chemistry applications. This bench-stable derivative serves as a key building block in the synthesis of targeted therapeutics and functionalized heterocycles.
4-Fluoro-1H-indole-2-carboxylic acid serves as a versatile building block for the synthesis of bioactive indole derivatives, particularly in medicinal chemistry and agrochemical research. The molecule combines a fluorinated aromatic ring with a carboxylic acid group, enabling direct coupling reactions, amide formation, and derivatization under standard conditions. Its bench-stable nature and compatibility with common protecting group strategies facilitate efficient access to complex heterocyclic scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: