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Structure of 1134524-25-6
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1-(4-Fluorophenyl)cyclopropanamine hydrochloride features a rigid cyclopropyl ring fused to a fluorinated phenyl group, delivering enhanced metabolic stability and improved membrane permeability. This bench-stable derivative serves as a key building block in medicinal chemistry for CNS-targeted therapeutics, where its electron-withdrawing fluorine substituent modulates bioavailability and target engagement.
1-(4-Fluorophenyl)cyclopropanamine hydrochloride serves as a valuable building block in medicinal chemistry, enabling the synthesis of bioactive compounds through standard amine functionalization. The cyclopropyl ring imparts conformational rigidity, while the para-fluoro substituent enhances metabolic stability and modulates electronic properties. This compound exhibits excellent bench stability, ease of handling, and compatibility with common coupling reactions, facilitating efficient incorporation into diverse heterocyclic scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: