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Structure of 113512-57-5
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2,4-Difluoro-5-nitrophenol features a fluorinated aromatic scaffold bearing electron-withdrawing nitro and fluoro substituents, enabling enhanced reactivity in cross-coupling and electrophilic substitution reactions. The para-nitro group stabilizes the phenolic form while the ortho-fluorines facilitate directed metalation and palladium-catalyzed functionalization. This bench-stable compound serves as a key building block for advanced pharmaceutical intermediates and agrochemicals.
2,4-Difluoro-5-nitrophenol serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to fluorinated heterocycles and functionalized aromatic scaffolds. Its dual electron-withdrawing substituents enhance electrophilicity for nucleophilic aromatic substitution, while the phenolic OH facilitates direct coupling or derivatization. The compound exhibits good bench stability and compatibility with standard reaction conditions, supporting scalable transformations in complex molecule assembly.
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GHS Pictogram :
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GHS No : GHS05,GHS07,GHS09
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Signal Word : Danger
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UN#: 3077
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Class : 9
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H317-H318-H410
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Precautionary Statements : P261-P264-P270-P272-P273-P280-P302+P352-P330-P362+P364-P391-P501
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Lot numbers can be found on the outside label of a product: