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Structure of 113512-71-3
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5-Amino-2,4-difluorophenol delivers a strategically positioned amino group flanked by two fluorine substituents, enabling enhanced electron donation and metabolic stability. This trifunctional phenolic scaffold integrates readily into bioactive molecule design, particularly in kinase inhibitors and pharmaceutical intermediates where halogenation and polarity balance are critical.
5-Amino-2,4-difluorophenol serves as a versatile building block in medicinal chemistry, enabling direct incorporation of amino and phenolic functionalities into complex scaffolds. Its ortho-fluorine substituents facilitate subsequent palladium-catalyzed cross-coupling reactions, while the amine group offers straightforward derivatization via acylation or alkylation. The compound exhibits good bench stability and is compatible with standard purification methods, making it well-suited for use in API synthesis and heterocycle construction.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: