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Structure of 100367-48-4
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5-Amino-2-fluorophenol features a fluorine atom at the ortho position relative to a hydroxyl group, creating a unique electronic profile that enhances reactivity in coupling processes. The amino group enables direct functionalization, while the phenolic moiety supports hydrogen bonding and solubility in polar solvents. This compound serves as a key building block for bioactive molecules and advanced materials, particularly in pharmaceutical intermediates and agrochemicals.
5-Amino-2-fluorophenol serves as a valuable building block in the synthesis of fluorinated aromatic scaffolds, enabling direct access to substituted anilines and heterocycles. Its ortho-amino and hydroxyl groups offer complementary reactivity for coupling reactions, cyclizations, and derivatization, with demonstrated utility in medicinal chemistry and agrochemical research. The compound exhibits good bench stability and facilitates straightforward purification via recrystallization or column chromatography.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H318
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501
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Lot numbers can be found on the outside label of a product: