Furo[2,3-c]pyridin-7-amine

Name: Furo[2,3-c]pyridin-7-amine
Brand: ChemScene
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CAS No. 1140240-20-5
Cat. No. CS-0196515
Molecule weight134.14
Purity≥95%
MDL No.None

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FedEx Limited Quantities Ground	$0.00
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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General Information

CAS No. 1140240-20-5
Cat. No. CS-0196515
Purity ≥95%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₆N₂O
Molecular Weight 134.14
Synonym(s) None
SMILES N=1C=CC=2C=COC2C1N

Description

Furo[2,3-c]pyridin-7-amine features a fused bicyclic core integrating furan and pyridine rings, delivering enhanced electron density at the amine site. This scaffold enables direct incorporation into bioactive molecules, serving as a key building block in medicinal chemistry for targeted kinase inhibitors and CNS-active compounds. The nitrogen-rich framework supports efficient derivatization under standard coupling conditions.

Application

Furo[2,3-c]pyridin-7-amine serves as a versatile heterocyclic building block for medicinal chemistry and materials science. Its fused tricyclic structure provides a rigid, planar scaffold with defined regiochemistry, enabling selective functionalization at the amine position. The compound exhibits good bench stability and facilitates direct coupling reactions, including Suzuki-Miyaura and Buchwald-Hartwig aminations, making it valuable for constructing complex molecular architectures in drug discovery and advanced organic synthesis.

Safety Information

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GHS Pictogram :	GHS No : GHS05
Signal Word : Danger	UN#: 3259
Class : 8	Packing Group : Ⅲ
Hazard Statements : H302-H314
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 52.05
LogP 1.41
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Furan compounds

Key Words

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Furo[2,3-c]pyridin-7-amine

CAS No. 1140240-20-5

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