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Structure of 1146629-84-6
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(R)-3-cyclopentyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanenitrile features a chiral nitrile-bearing scaffold paired with a boronate ester handle, enabling efficient Suzuki-Miyaura cross-coupling. The cyclopentyl group imparts steric bulk and enhanced metabolic stability, while the tetramethyl-substituted dioxaborolane ensures excellent shelf life and moisture tolerance under standard conditions. This compound serves as a key building block for bioactive heterocycles in medicinal chemistry.
(R)-3-cyclopentyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanenitrile serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The pyrazole-boronate moiety enables efficient C–C bond formation under mild conditions, while the chiral nitrile-bearing cyclopentyl group provides structural rigidity and functional handle diversity. Bench-stable and compatible with diverse reaction conditions, it facilitates the construction of complex heterocyclic scaffolds in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: