2-Amino-6-fluorobenzamide

Name: 2-Amino-6-fluorobenzamide
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 115643-59-9
Cat. No. CS-0186546
Purity≥98%
MDL No.None

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Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

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Description

2-Amino-6-fluorobenzamide features a fluorine atom at the para position relative to the amide group, enhancing electronic effects and metabolic stability. The amino group enables direct coupling in peptide synthesis and conjugation workflows. This bench-stable derivative integrates readily into bioactive scaffolds for medicinal chemistry campaigns.

Application

2-Amino-6-fluorobenzamide serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles and peptide-like scaffolds. Its ortho-amino and fluoro substituents provide complementary reactivity for palladium-catalyzed couplings, electrophilic substitutions, and cyclization reactions. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for scalable synthesis and API development workflows.

General Information

CAS No. 115643-59-9
Cat. No. CS-0186546
Purity ≥98%
MDL No. None
Storage RT, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₇FN₂O
Molecular Weight 154.14
Synonym(s) None
SMILES NC1=CC=CC(F)=C1C(N)=O

Computational Chemistry Data

TPSA 69.11
LogP 0.5068
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Fluoride

Building Blocks Functional Group Amide

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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2-Amino-6-fluorobenzamide

CAS No. 115643-59-9

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