6-Bromo-4-methoxypyridin-2-amine

Name: 6-Bromo-4-methoxypyridin-2-amine
Brand: ChemScene
Availability: InStock
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CAS No. 1158786-59-4
Cat. No. CS-0107192
Purity≥97%
MDL No.MFCD20040422

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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6-Bromo-4-methoxypyridin-2-amine|CS-0107192

Structure of 1158786-59-4

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Description

6-Bromo-4-methoxypyridin-2-amine features a pyridine core bearing bromo and methoxy substituents at electron-deficient positions, enabling selective cross-coupling reactions. The amine functionality facilitates direct incorporation into bioactive scaffolds, while the molecule exhibits robust stability under standard conditions.

Application

6-Bromo-4-methoxypyridin-2-amine serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyridine-based scaffolds through palladium-catalyzed cross-coupling reactions. The bromo group facilitates reliable C–C and C–N bond formation, while the methoxy and amino functionalities provide orthogonal reactivity for sequential functionalization. Bench-stable and readily purified, it supports scalable synthesis of kinase inhibitors, antiviral agents, and other heterocyclic APIs.

General Information

CAS No. 1158786-59-4
Cat. No. CS-0107192
Purity ≥97%
MDL No. MFCD20040422
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₇BrN₂O
Molecular Weight 203.04
Synonym(s) 2-aMino-6-broMo-4-Methoxypyridine
SMILES COC1=CC(N)=NC(Br)=C1

Computational Chemistry Data

TPSA 48.14
LogP 1.4349
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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6-Bromo-4-methoxypyridin-2-amine

CAS No. 1158786-59-4

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