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Structure of 1166820-07-0
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tert-Butyl 6,6-difluoro-1,4-diazepane-1-carboxylate features a sterically shielded, bench-stable diazepane core bearing two fluorine atoms at the 6-position. This electron-deficient heterocycle integrates readily into medicinal chemistry scaffolds, offering enhanced metabolic stability and modulated basicity. The tert-butyl ester group enables convenient deprotection under mild acidic conditions.
tert-Butyl 6,6-difluoro-1,4-diazepane-1-carboxylate serves as a valuable building block in medicinal chemistry, enabling the incorporation of a rigid, electron-deficient diazepane scaffold into bioactive molecules. The difluorinated ring enhances metabolic stability and modulates basicity, while the tert-butoxycarbonyl group provides convenient protection for amine-directed transformations. Its bench-stable nature and compatibility with standard coupling and deprotection protocols facilitate efficient synthesis of complex heterocyclic targets.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: