(R)-1-(2-Fluorophenyl)ethanamine hydrochloride

Name: (R)-1-(2-Fluorophenyl)ethanamine hydrochloride
Brand: ChemScene
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CAS No. 1168139-43-2
Cat. No. CS-0043725
Purity≥95%
MDL No.MFCD11101199

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(R)-1-(2-Fluorophenyl)ethanamine hydrochloride|CS-0043725

Structure of 1168139-43-2

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Description

(R)-1-(2-Fluorophenyl)ethanamine hydrochloride is a chiral amine featuring a fluorinated aromatic ring and a stereodefined primary amine. This bench-stable salt integrates readily into asymmetric synthesis, serving as a high-purity building block for pharmaceutical intermediates and functionalized ligands.

Application

(R)-1-(2-Fluorophenyl)ethanamine hydrochloride serves as a chiral building block for pharmaceutical intermediates, enabling stereoselective synthesis of bioactive molecules. Its bench-stable hydrochloride salt form facilitates handling and purification, while the ortho-fluorophenyl group offers enhanced metabolic stability and modulated electronic properties. Functions effectively in amine coupling, reductive amination, and transition-metal-catalyzed cross-coupling reactions, supporting scalable route development in medicinal chemistry and process R&D.

General Information

CAS No. 1168139-43-2
Cat. No. CS-0043725
Purity ≥95%
MDL No. MFCD11101199
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₁₁ClFN
Molecular Weight 175.63
Synonym(s) (R)-1-(2-Fluorophenyl)ethylamine hydrochloride
SMILES N[C@@H](C1=CC=CC=C1F)C.[H]Cl

Computational Chemistry Data

TPSA 26.02
LogP 2.2672
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Fluoride

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-1-(2-Fluorophenyl)ethanamine hydrochloride

CAS No. 1168139-43-2

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