(R)-1-(2,6-Difluorophenyl)ethanamine hydrochloride

Name: (R)-1-(2,6-Difluorophenyl)ethanamine hydrochloride
Brand: ChemScene
Availability: InStock
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CAS No. 1309598-72-8
Cat. No. CS-0158208
Purity≥97%
MDL No.MFCD12757707

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(R)-1-(2,6-Difluorophenyl)ethanamine hydrochloride|CS-0158208

Structure of 1309598-72-8

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Description

(R)-1-(2,6-Difluorophenyl)ethanamine hydrochloride is a chiral amine featuring a sterically hindered aryl moiety with fluorine substituents at the 2- and 6-positions. This configuration imparts enhanced metabolic stability and favorable binding affinity in asymmetric synthesis. The hydrochloride salt form ensures high solubility and ease of handling under standard bench conditions.

Application

(R)-1-(2,6-Difluorophenyl)ethanamine hydrochloride serves as a chiral building block for pharmaceutical intermediates, enabling efficient access to bioactive scaffolds via amine coupling and cyclization reactions. The difluorophenyl moiety enhances metabolic stability and modulates lipophilicity, while the hydrochloride salt ensures excellent bench stability, ease of handling, and compatibility with standard purification methods in synthetic workflows.

General Information

CAS No. 1309598-72-8
Cat. No. CS-0158208
Purity ≥97%
MDL No. MFCD12757707
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₁₀ClF₂N
Molecular Weight 193.62
Synonym(s) (R)-1-(2,6-Difluorophenyl)ethylamine hydrochloride
SMILES C[C@H](C1=C(C=CC=C1F)F)N.Cl

Computational Chemistry Data

TPSA 26.02
LogP 2.4063
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Other Classifications

Building Blocks Functional Group Fluoride

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-1-(2,6-Difluorophenyl)ethanamine hydrochloride

CAS No. 1309598-72-8

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