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Structure of 1174020-48-4
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This tert-butyl (3S,4R)-3-fluoro-4-hydroxypyrrolidine-1-carboxylate features a stereochemically defined fluorinated pyrrolidine core with a bench-stable tert-butyl ester handle. The 3-fluoro, 4-hydroxy motif enables direct incorporation into bioactive scaffolds requiring conformational restraint and enhanced metabolic stability. This derivative pairs well with coupling reactions under mild conditions, offering efficient access to fluorinated heterocycles in medicinal chemistry campaigns.
tert-Butyl (3S,4R)-3-fluoro-4-hydroxypyrrolidine-1-carboxylate serves as a stereochemically defined building block for fluorinated pyrrolidine scaffolds. The hydroxyl group enables selective derivatization, while the tert-butyl carbamate offers stability and convenient removal under mild acidic conditions. This compound functions effectively in late-stage functionalization and supports the synthesis of bioactive heterocycles via standard coupling and cyclization protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: