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Structure of 2006333-41-9
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trans-4-Fluoropyrrolidin-3-ol hydrochloride features a conformationally constrained pyrrolidine ring with a fluorine atom at the 4-position, imparting enhanced metabolic stability and improved membrane permeability. This bench-stable, moisture-tolerant compound integrates readily into bioactive molecule scaffolds for medicinal chemistry applications.
trans-4-Fluoropyrrolidin-3-ol hydrochloride serves as a key chiral building block in medicinal chemistry, enabling the synthesis of fluorinated pyrrolidine scaffolds prevalent in bioactive molecules. Its bench-stable hydrochloride salt form facilitates handling and purification, while the trans stereochemistry ensures predictable conformational behavior in downstream transformations. The molecule exhibits robust functional group tolerance and functions effectively in amide coupling, nucleophilic substitution, and cyclization reactions critical to API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: