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Structure of 117832-15-2
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4-Iodo-3,5-dimethylaniline features a sterically hindered aromatic core with electron-donating methyl groups flanking a reactive iodo substituent. This configuration enhances stability while enabling efficient coupling in cross-coupling reactions. The molecule’s bench-stable nature and predictable reactivity make it a reliable building block for pharmaceutical intermediates and functional materials synthesis under standard conditions.
4-Iodo-3,5-dimethylaniline serves as a versatile building block for Suzuki-Miyaura coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. Its ortho-methyl groups provide steric protection and enhance bench stability, while the iodine handle offers high reactivity in palladium-catalyzed transformations. The dimethyl substitution pattern confers excellent functional group tolerance and facilitates straightforward purification, making it ideal for medicinal chemistry and process-scale synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: