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Structure of 89938-16-9
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2-Iodo-3-methylaniline features a strategically positioned iodine atom adjacent to a methyl-substituted aniline ring, enabling direct functionalization in cross-coupling reactions. This bench-stable derivative combines enhanced reactivity with predictable regiochemistry, streamlining access to substituted arylamines in pharmaceutical and materials synthesis.
2-Iodo-3-methylaniline serves as a versatile building block in medicinal chemistry and cross-coupling reactions, offering reliable functionality for Suzuki-Miyaura and Buchwald-Hartwig transformations. The iodine atom enables efficient palladium-catalyzed coupling, while the ortho-iodo and meta-methyl groups provide predictable regioselectivity and enhanced stability under standard reaction conditions. Its bench-stable nature and compatibility with diverse functional groups make it well-suited for modular synthesis of complex heterocycles and pharmaceutical intermediates.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: