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CS-W001157 4
Total: USD 88.00

(4-Cyclopropylphenyl)methanamine

  • CAS No. 118184-67-1

  • Cat. No. CS-0202401
  • Molecule weight147.22
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(4-Cyclopropylphenyl)methanamine|CS-0202401

Structure of 118184-67-1

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General Information

  • CAS No. 118184-67-1
  • Cat. No. CS-0202401
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₃N
  • Molecular Weight 147.22
  • Synonym(s) p-Cyclopropylbenzylamine
  • SMILES NCC1=CC=C(C2CC2)C=C1

Description

(4-Cyclopropylphenyl)methanamine features a cyclopropyl-substituted aromatic ring linked to a primary amine group, delivering enhanced lipophilicity and metabolic stability. This scaffold integrates readily into bioactive molecules, particularly in kinase inhibitors and CNS-targeted pharmaceuticals. The compound exhibits robust bench stability and compatibility with standard synthetic protocols.

Application

(4-Cyclopropylphenyl)methanamine serves as a valuable building block in medicinal chemistry, enabling the synthesis of bioactive compounds through standard amine functionalization. Its cyclopropyl-substituted aromatic core provides enhanced metabolic stability and favorable lipophilicity profiles. The primary amine functionality facilitates straightforward derivatization via acylation, alkylation, or coupling reactions, while the compound exhibits good bench stability and ease of purification—making it well-suited for high-throughput screening campaigns and process-scale applications.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.0227
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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