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Structure of 1197956-03-8
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This dimethylphosphine oxide features a 4-amino-3-methoxyphenyl group, delivering enhanced solubility and stability in polar solvents. The phosphine oxide moiety provides strong coordination ability while maintaining bench-stable handling characteristics. Ideal for catalytic applications requiring electron-rich yet moisture-tolerant ligands.
(4-Amino-3-methoxyphenyl)dimethylphosphine oxide serves as a versatile phosphine-based building block in transition-metal-catalyzed cross-coupling reactions. Its electron-donating amino and methoxy groups enhance reactivity while the phosphine oxide functionality provides stability and facilitates purification. This compound enables efficient Pd-catalyzed C–C and C–heteroatom bond formations, particularly in the synthesis of functionalized biaryl and heterocyclic scaffolds common in medicinal chemistry.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: