Desamino lenalidomide-NO2

Name: Desamino lenalidomide-NO2
Brand: ChemScene
Availability: InStock
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CAS No. 1198787-23-3
Cat. No. CS-0614434
Purity≥98%
MDL No.MFCD33404278

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 1198787-23-3

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Description

This piperidine-2,6-dione scaffold features a 5-nitro-1-oxoisoindoline moiety that imparts strong electron-withdrawing character, enhancing reactivity in conjugate addition and cycloaddition processes. The fused ring system provides rigidity and defined spatial orientation, enabling precise molecular positioning in synthetic intermediates. Bench-stable under standard conditions, it integrates readily into complex heterocyclic architectures.

Application

3-(5-Nitro-1-oxoisoindolin-2-yl)piperidine-2,6-dione serves as a versatile scaffold for constructing bioactive heterocycles, leveraging the electron-deficient isoindolinone core and flanking diketone functionality. The nitro group enhances electrophilicity for nucleophilic addition, while the piperidinedione moiety provides a rigid, polar framework suitable for metal-catalyzed coupling and solid-phase synthesis. This compound enables efficient access to complex polycyclic systems under standard bench conditions, exhibiting robust stability and compatibility with common functional groups.

General Information

CAS No. 1198787-23-3
Cat. No. CS-0614434
Purity ≥98%
MDL No. MFCD33404278
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₃H₁₁N₃O₅
Molecular Weight 289.24
Synonym(s) None
SMILES O=C1C2=CC=C([N+]([O-])=O)C=C2CN1C3C(NC(CC3)=O)=O

Computational Chemistry Data

TPSA 112.3
LogP -0.9826
H_Acceptors 7
H_Donors 1
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Indolin compounds

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Life Science PROTAC Ligands for E3 Ligase

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Proteolysis Targeting Chimera Research Reagents

Biochemistry Pharmaceutical Development and Drug Discovery Research Proteolysis Targeting Chimera Research Reagents

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Desamino lenalidomide-NO2

CAS No. 1198787-23-3

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