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Structure of 120218-45-3
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1-Phenylcyclobutanamine hydrochloride features a rigid cyclobutane scaffold bearing a primary amine and phenyl group, delivering enhanced metabolic stability compared to linear analogs. This bench-stable salt form ensures reliable handling and solubility in aqueous systems, enabling direct incorporation into medicinal chemistry campaigns targeting CNS-directed therapeutics and receptor modulators.
1-Phenylcyclobutanamine hydrochloride serves as a valuable chiral building block for medicinal chemistry, enabling the synthesis of bioactive scaffolds through standard amine functionalization. Its cyclobutane core provides conformational rigidity beneficial for structure-activity studies, while the hydrochloride salt ensures excellent bench stability and ease of handling. The compound readily participates in nucleophilic substitution, reductive amination, and coupling reactions, facilitating efficient access to diverse heterocyclic and peptide-like architectures under routine laboratory conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: