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CS-W001157 4
Total: USD 88.00

(2-Aminopyridin-3-yl)boronic acid

  • CAS No. 1204112-62-8

  • Cat. No. CS-0174006
  • Purity≥97%
  • MDL No.MFCD11865292
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(2-Aminopyridin-3-yl)boronic acid|CS-0174006

Structure of 1204112-62-8

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Description

This boronate moiety integrates seamlessly into Suzuki-Miyaura cross-coupling reactions, offering enhanced reactivity and stability under standard conditions. The ortho-aminopyridyl group enables efficient coordination in catalytic systems, facilitating selective functionalization of heteroaromatic scaffolds with minimal side-product formation.

Application

(2-Aminopyridin-3-yl)boronic acid serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. Its ortho-amino functionality enhances coordination to palladium catalysts and improves reaction efficiency in Suzuki-Miyaura coupling. The boronic acid moiety offers excellent bench stability, facile purification, and compatibility with diverse functional groups, making it ideal for constructing biologically relevant heterocyclic scaffolds in medicinal chemistry and materials science applications.

General Information

  • CAS No. 1204112-62-8
  • Cat. No. CS-0174006
  • Purity ≥97%
  • MDL No. MFCD11865292
  • Storage -20°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₇BN₂O₂
  • Molecular Weight 137.93
  • Synonym(s) 2-Aminopyridine-3-boronic acid·2HCl2
  • SMILES NC1=C(B(O)O)C=CC=N1

Computational Chemistry Data

  • TPSA   79.37
  • LogP   -1.6564
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   1

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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