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Structure of 1206640-82-5
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1-(Difluoromethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole integrates a difluoromethyl group with a stable boronate handle, enabling direct coupling in Suzuki-Miyaura reactions. The tetramethyl-substituted dioxaborolane enhances shelf life and moisture tolerance, while the pyrazole core provides a rigid, electron-deficient scaffold for diverse heterocyclic synthesis.
1-(Difluoromethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole serves as a versatile boronate building block for Suzuki-Miyaura coupling reactions. The difluoromethyl group imparts enhanced metabolic stability and modulates electronic properties, while the pinacol boronate enables robust reaction conditions, excellent functional group tolerance, and straightforward purification. This compound facilitates efficient construction of pyrazole-based scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H315-H318-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: