Sorafenib impurity 6

Name: Sorafenib impurity 6
Brand: ChemScene
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CAS No. 1209459-88-0
Cat. No. CS-0160795
Purity≥97%
MDL No.MFCD14702606

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 1209459-88-0

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Description

4-Bromo-N-methylpicolinamide features a bromine atom at the pyridine 4-position and a methylamino group on the nitrogen, delivering enhanced reactivity in cross-coupling transformations. This bench-stable, moisture-tolerant building block integrates efficiently into complex molecular architectures under standard conditions.

Application

4-Bromo-N-methylpicolinamide serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its stable bromo group and amide functionality. The N-methylpyridine-4-carboxamide core provides excellent compatibility with standard coupling protocols, facilitating the construction of complex heterocyclic scaffolds. Bench-stable and readily purified by column chromatography, it functions efficiently in late-stage functionalization and API intermediate synthesis.

General Information

CAS No. 1209459-88-0
Cat. No. CS-0160795
Purity ≥97%
MDL No. MFCD14702606
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₇BrN₂O
Molecular Weight 215.05
Synonym(s) None
SMILES O=C(NC)C1=NC=CC(Br)=C1

Computational Chemistry Data

TPSA 41.99
LogP 1.2037
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Amide

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

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Sorafenib impurity 6

CAS No. 1209459-88-0

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