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tert-butyl 2-amino-6,7-dihydropyrazolo[1,5-a]pyrazine-5(4H)-carboxylate

  • CAS No. 1209487-56-8

  • Cat. No. CS-0199612
  • Purity≥95%
  • MDL No.MFCD27938022

*For research and further manufacturing use only, not for direct human use.

tert-butyl 2-amino-6,7-dihydropyrazolo[1,5-a]pyrazine-5(4H)-carboxylate|CS-0199612

Structure of 1209487-56-8

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General Information

  • CAS No. 1209487-56-8
  • Cat. No. CS-0199612
  • Purity ≥95%
  • MDL No. MFCD27938022
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₈N₄O₂
  • Molecular Weight None
  • Synonym(s) ZFTDHMFOVBQLSF-UHFFFAOYSA-N
  • SMILES O=C(OC(C)(C)C)N1CC2=CC(=NN2CC1)N

Description

tert-butyl 2-amino-6,7-dihydropyrazolo[1,5-a]pyrazine-5(4H)-carboxylate features a fused pyrazolo-pyrazine core with a reducible dihydropyrazine moiety and a bench-stable tert-butyl ester. This scaffold integrates readily into medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds, offering favorable solubility and compatibility with standard amine derivatization protocols.

Application

tert-Butyl 2-amino-6,7-dihydropyrazolo[1,5-a]pyrazine-5(4H)-carboxylate serves as a versatile heterocyclic building block for medicinal chemistry and synthetic organic applications. The compound features a fused pyrazolo[1,5-a]pyrazine core with a readily modifiable amino group and a stable tert-butyl ester, enabling selective transformations. Its bench-stable nature and compatibility with standard coupling and functionalization protocols facilitate efficient access to complex scaffolds in API development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362+P364

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Computational Chemistry Data

  • TPSA   73.38
  • LogP   1.216
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   0

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