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Structure of 1211580-84-5
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5-Bromo-3-(trifluoromethyl)picolinic acid features a strategically positioned trifluoromethyl group and bromine substituent on the picolinic acid scaffold, delivering enhanced electron-withdrawal and enabling direct functionalization in cross-coupling reactions. This bench-stable derivative serves as a key building block for bioactive heterocycles and pharmaceutical intermediates.
5-Bromo-3-(trifluoromethyl)picolinic acid serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling direct functionalization at the C5 position via palladium-catalyzed cross-coupling reactions. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the carboxylic acid moiety facilitates derivatization through amide formation or esterification. Its bench-stable crystalline form and compatibility with standard reaction conditions make it ideal for iterative synthetic campaigns targeting heterocyclic scaffolds and bioactive molecules.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H320-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: