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Structure of 87407-12-3
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3-(Trifluoromethyl)picolinic acid features a trifluoromethyl group at the 3-position of the picolinic acid scaffold, delivering enhanced electron-withdrawing character and improved metabolic stability. This structural motif enables robust coupling in peptide synthesis and facilitates integration into bioactive molecules requiring high lipophilicity and resistance to oxidative degradation.
3-(Trifluoromethyl)picolinic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its trifluoromethyl group imparts enhanced metabolic stability and lipophilicity, while the pyridine carboxylic acid core facilitates diverse transformations including amidation, esterification, and coupling reactions. The compound exhibits good bench stability and is compatible with standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: