(S)-1-(2-Methoxypyridin-4-yl)ethanamine

Name: (S)-1-(2-Methoxypyridin-4-yl)ethanamine
Brand: ChemScene
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CAS No. 1212853-72-9
Cat. No. CS-0158261
Purity≥98%
MDL No.MFCD11859029

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(S)-1-(2-Methoxypyridin-4-yl)ethanamine|CS-0158261

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General Information

CAS No. 1212853-72-9
Cat. No. CS-0158261
Purity ≥98%
MDL No. MFCD11859029
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₁₂N₂O
Molecular Weight 152.19
Synonym(s) AZ (S)-1-(2-METHOXYPYRIDIN-4-YL)ETHANAMINE
SMILES C[C@@H](C1=CC(=NC=C1)OC)N

Description

(S)-1-(2-Methoxypyridin-4-yl)ethanamine features a chiral ethylamine side chain attached to a methoxypyridine scaffold, enabling selective functionalization in asymmetric synthesis. This bench-stable, moisture-tolerant amine integrates readily into pharmaceutical intermediates and ligand design, offering high stereocontrol in transition-metal-catalyzed transformations.

Application

(S)-1-(2-Methoxypyridin-4-yl)ethanamine serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of pyridine-containing pharmaceutical intermediates. Its well-defined stereochemistry and stable pyridine core facilitate efficient coupling reactions and functional group manipulations. The methoxy substituent enhances solubility and modulates electronic properties, while the amine functionality supports straightforward derivatization via acylation, alkylation, or salt formation—making it suitable for high-throughput screening and process-scale synthesis.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

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Computational Chemistry Data

TPSA 48.14
LogP 1.1099
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 2

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(S)-1-(2-Methoxypyridin-4-yl)ethanamine

CAS No. 1212853-72-9

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