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Structure of 1214358-05-0
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4-(Difluoromethoxy)-2-fluorobenzaldehyde features a strategically positioned aldehyde group flanked by electron-withdrawing fluorine and difluoromethoxy substituents, enhancing reactivity in cross-coupling and electrophilic substitution reactions. This bench-stable aromatic aldehyde integrates readily into complex molecular architectures requiring precise electronic tuning.
4-(Difluoromethoxy)-2-fluorobenzaldehyde serves as a versatile building block in medicinal chemistry, enabling the construction of fluorinated aromatic scaffolds via standard coupling reactions. Its ortho-fluoro and difluoromethoxy substituents provide enhanced metabolic stability and modulated electronic properties. The aldehyde functionality facilitates efficient derivatization through reductive amination, Grignard additions, or condensation reactions, offering reliable access to complex target molecules with high functional group tolerance and bench stability.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: