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Structure of 1214361-39-3
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3-Bromo-6-(trifluoromethyl)pyridin-2-amine features a bromine atom at the 3-position and a trifluoromethyl group at the 6-position of a pyridine ring bearing a primary amine at the 2-position. This electron-deficient heterocycle enables direct functionalization in cross-coupling reactions, serving as a key scaffold for pharmaceutical intermediates and advanced ligands.
3-Bromo-6-(trifluoromethyl)pyridin-2-amine serves as a versatile building block for constructing bioactive heterocycles, enabling palladium-catalyzed cross-coupling reactions with broad functional group tolerance. The bromo and amino groups provide orthogonal reactivity for sequential modifications, while the trifluoromethyl substituent enhances metabolic stability and lipophilicity—key attributes in medicinal chemistry. Its bench-stable crystalline form facilitates handling and purification, making it well-suited for scalable synthesis of pharmaceutical intermediates and kinase inhibitor scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: