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Structure of 1220039-52-0
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Methyl 4-fluoro-1H-indole-3-carboxylate features a fluorinated indole core with a methyl ester at the 3-position, offering enhanced electronic modulation and metabolic stability. This bench-stable compound integrates readily into synthetic routes for bioactive molecules, particularly in medicinal chemistry and pharmaceutical development workflows.
Methyl 4-fluoro-1H-indole-3-carboxylate serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. The ortho-fluorine substituent enables directed metalation and facilitates late-stage functionalization via cross-coupling reactions. Its methyl ester group offers compatibility with standard reduction, hydrolysis, and amidation protocols, while the indole core provides inherent stability and favorable reactivity in electrophilic substitution and transition-metal-catalyzed transformations.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: