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Structure of 1227268-61-2
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Methyl 5-fluoro-1H-indole-6-carboxylate features a fluorinated indole core with a strategically positioned ester group, enabling direct functionalization in late-stage synthesis. The electron-deficient aromatic system enhances reactivity in transition-metal-catalyzed couplings, while the methyl ester offers stability and ease of manipulation under standard conditions.
Methyl 5-fluoro-1H-indole-6-carboxylate serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. The fluorine substituent enhances metabolic stability and modulates electronic properties, while the ester group enables straightforward functionalization via hydrolysis, reduction, or coupling reactions. Its bench-stable nature and compatibility with standard synthetic protocols make it well-suited for medicinal chemistry campaigns and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H320-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: