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Structure of 1227562-37-9
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5-Bromo-2-hydroxyisonicotinaldehyde features a strategically positioned bromine atom and a reactive aldehyde group flanked by a hydroxyl moiety, enabling direct incorporation into heterocyclic scaffolds. This electron-deficient pyridine derivative facilitates efficient coupling reactions under mild conditions, offering high functional group tolerance and enhanced solubility in polar aprotic solvents.
5-Bromo-2-hydroxyisonicotinaldehyde serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted heterocycles and bioactive scaffolds. Its ortho-hydroxy aldehyde functionality facilitates intramolecular cyclizations and metal-catalyzed coupling reactions, while the bromine substituent supports further functionalization via palladium-mediated transformations. The compound exhibits bench stability and compatibility with common protecting group strategies, making it well-suited for iterative synthesis in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P261-P280-P304+P340
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Lot numbers can be found on the outside label of a product: