4-Bromo-2-fluoro-5-methylpyridine

Name: 4-Bromo-2-fluoro-5-methylpyridine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1227577-02-7
Cat. No. CS-0130950
Purity≥96%
MDL No.MFCD16609965

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Bromo-2-fluoro-5-methylpyridine|CS-0130950

Structure of 1227577-02-7

Size

Price

Quantity

* Please select Quantity before adding items.

Description

4-Bromo-2-fluoro-5-methylpyridine features a strategically positioned bromo and fluoro substituent on a methylated pyridine core, enabling selective cross-coupling reactions. The electron-deficient ring facilitates palladium-catalyzed transformations, while the methyl group enhances solubility and steric profile. This scaffold serves as a key intermediate in medicinal chemistry for kinase inhibitors and agrochemicals.

Application

4-Bromo-2-fluoro-5-methylpyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its complementary halogen reactivity. The fluorine and methyl groups provide orthogonal functional handles for further derivatization, while the pyridine core offers stability and favorable electronic properties for target-oriented synthesis. Its bench-stable nature and compatibility with standard reaction conditions facilitate efficient assembly of complex heterocyclic scaffolds.

General Information

CAS No. 1227577-02-7
Cat. No. CS-0130950
Purity ≥96%
MDL No. MFCD16609965
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₅BrFN
Molecular Weight 190.01
Synonym(s) None
SMILES CC1=CN=C(F)C=C1Br

Computational Chemistry Data

TPSA 12.89
LogP 2.29162
H_Acceptors 1
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

4-Bromo-2-fluoro-5-methylpyridine sigma4-Bromo-2-fluoro-5-methylpyridine manufacturer4-Bromo-2-fluoro-5-methylpyridine price4-Bromo-2-fluoro-5-methylpyridine structure4-Bromo-2-fluoro-5-methylpyridine SDSbuy 4-Bromo-2-fluoro-5-methylpyridine4-Bromo-2-fluoro-5-methylpyridine supplier4-Bromo-2-fluoro-5-methylpyridine uses4-Bromo-2-fluoro-5-methylpyridine molecular weightprice of 4-Bromo-2-fluoro-5-methylpyridine4-Bromo-2-fluoro-5-methylpyridine chemical name formula of 4-Bromo-2-fluoro-5-methylpyridine

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

4-Bromo-2-fluoro-5-methylpyridine

CAS No. 1227577-02-7

Recommended Products